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David Nathan was stunned when he first saw Dayem Saif at Children's Hospital in Boston in September 1968. Dayem was then a six-year-old with the stature of an average-sized boy of two. He wore baby shoes on his tiny feet and was unable to walk without holding his mother's hand. His color was dark yet pasty and his face horribly misshapen. The child was being ravaged by thalassemia, a life-threatening inherited disease of the blood, and one of the leading causes of disfigurement, disability, and death in children worldwide. Without effective treatment, Dayem would almost certainly die before his twentieth birthday.

Genes, Blood, and Courage is David Nathan's absorbing story of the thirty-year struggle to keep Dayem alive. "Immortal Sword" is the English translation of Dayem's Arabic name, and under Nathan's care Dayem, indeed, seems immortal. Despite his continual reluctance to follow his doctor's orders and the repeated hospitalizations that result, Dayem--the misshapen, stunted boy--survives to become a handsome, successful businessman.

In Genes, Blood, and Courage Nathan goes beyond his struggles with this seemingly immortal patient to describe in detail the emergence, over the past twenty-five years, of an entirely new force in medical care called molecular medicine. As Dayem's case illustrates, this new area of human genetic research--in which Nathan is a leading clinical investigator--promises tremendous advances in the rational diagnosis, prevention, and treatment of inherited disorders, such as thalassemia and sickle cell anemia, and even of acquired illnesses such as cancer and infectious disease.

Genes, Blood, and Courage is a celebration not just of Dayem's triumphs but also of the tremendous accomplishments and potential of the American biomedical research enterprise in the late twentieth century.

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This comprehensive yet concise book provides a thorough and complete guide to every aspect of managing the peer review process for scientific journals. Until now, little information has been readily available on how this important facet of the journal publishing process should be conducted properly. Peer Review and Manuscript Management in Scientific Journals fills this gap and provides clear guidance on all aspects of peer review, from manuscript submission to final decision.

Peer Review and Manuscript Management in Scientific Journals is an essential reference for science journal editors, editorial office staff and publishers. It is an invaluable handbook for the set-up of new Editorial Offices, as well as a useful reference for well-established journals which may need guidance on a particular situation, or may want to review their current practices. Although intended primarily for journals in science, much of its content will be relevant to other scholarly areas.

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?This wonderful work by Dr. Hames can be used as a textbook in courses for both experienced and novice editors, and I trust that it is what Dr. Hames intended when she prepared this beautiful book. Every scientific editor should read it.? Journal of Educational Evaluation for Health Professionals, 2008

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Discover how to use the Internet to locate primary sources for medical information. This focused guide zeros in on the most valuable sites and techniques for staying up-to-date on medical issues, grasping new technologies, and enhancing medical practice. Companion CD software Data.zip (1MB) Demos.zip (2.1MB) Resource.zip (1.4MB)

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Written by the editor of a cutting-edge nursing journal, Outcomes Management , this book doubles as a textbook for graduate students in nursing and as a reference book for nurses. Designed to describe the process of writing for publication, the book discusses writing various types of articles for publication in journals; structuring different types of articles; submitting materials; and strategies for dealing with editorial issues. Information about electronic publishing and writing for online journals is included. Useful features include summaries, reference lists, and online writing strategies. Chapter examples enliven text presentation.

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Aims to show the reader what research is, the tools and methods needed to conduct it, how to interpret and report the knowledge obtained, and how society may accept that knowledge. The text includes qualitative research and examples to help the reader appreciate these techniques. An instructor's manual and test item file are also available.

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Provides immediate help for anyone preparing a biomedical paper by givin specific advice on organizing the components of the paper, effective writing techniques, writing an effective results sections, documentation issues, sentence structure and much more. The new edition includes new examples from the current literature including many involving molecular biology, expanded exercises at the end of the book, revised explanations on linking key terms, transition clauses, uses of subheads, and emphases. If you plan to do any medical writing, read this book first and get an immediate advantage.

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Transforming biological discoveries into medical treatment calls for a cadre of health professionals skilled in patient-oriented research. Yet many factors discourage talented persons from choosing clinical research as a profession.
This new volume lays out the problem in detail, with specific recommendations to the federal government, the biotechnology and pharmaceutical industries, professional organizations, the health care industry, organized medicine, and the nation's universities and academic health centers.
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This practical book will be of immediate interest to public and private agencies funding research, research administrators, medical educators, health professionals, and those pursuing a career in clinical investigation.

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Designing and Conducting Research in Health and Human Performance Reviews

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Designing and Conducting Research in Health and Human Performance shows students how to become effective producers and consumers of health and human performance research. The book provides comprehensive coverage of both quantitative and qualitative research methods and includes step-by-step guidance for writing effective research proposals and theses. In addition, the authors show how to read, assess, interpret, and apply published research and how to conduct basic studies in health, physical education, exercise science, athletic training, and recreation.

Designing and Conducting Research in Health and Human Performance is filled with illustrative examples that emphasize the real-world applications of research methods. Throughout, the authors draw on a variety of examples that were selected because they provide a context to further the understanding of health and human performance research.

Research to Practice examples and Tips are included by the authors to help students better appreciate the book's content. These study aids provide suggestions and additional resources to assist students in understanding the research process. Key Terms, defined and highlighted, enrich each chapter. Chapter Review Questions, designed to help students comprehend and follow best practices in research methods, close each chapter. Online resources and guides developed by the authors to support and enhance students' learning of important research concepts are available.

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Cut Through the Complexities of Medical Studies!

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Enhance your understanding and utilization of the information in medical journals with Stephen Gehlbach's Interpreting the Medical Literature. Written in a clear and entertaining style, this popular guide cuts through the complex language of research studies and makes reading medical publications a rewarding and pleasurable experience.

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New to the Fifth Edition: a chapter on how to interpret conflicting studies; expanded discussions of meta-analysis and developing consensus; updated figures and charts

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Understanding Health Care Outcomes Research by Jones & Bartlett Pub




The first edition of this ground-breaking book was the pioneer text on outcomes research. It's a resource no quality-minded health care professional should be without. Both practical and applied, this book makes sense of the new science of studying health care outcomes - a vital process in health care quality assurance. Understanding Health Care Outcomes Research, Second Edition, gives readers a wealth of expert advice on the basic framework needed to conduct any type of outcomes research, formulating the model, choosing the study design, developing meaningful measures, gathering data, and assessing and presenting results. The second edition includes new chapters on confounders, research design, and working within clinical settings. All chapters have been updated. Understanding Health Care Outcomes Research, Second Edition includes more attention to larger interventions that include population level changes.Read more Understanding Health Care Outcomes Research

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In his bestselling guide, Doing Honest Work in College: How to Prepare Citations, Avoid Plagiarism, and Achieve Real Academic Success, veteran teacher Charles Lipson brought welcome clarity to the principles of academic honesty as well as to the often murky issues surrounding plagiarism in the digital age.  Thousands of students have turned to Lipson for no-nonsense advice on how to cite sources properly—and avoid plagiarism—when writing their research papers. With his latest book, Cite Right, Lipson once again provides much-needed counsel in a concise and affordable handbook for students and researchers. Building on Doing Honest Work in College, Lipson’s new book offers a wealth of information on an even greater range of citation styles and details the intricacies of many additional kinds of sources. 

 

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Life science data integration and interoperability is one of the most challenging problems facing bioinformatics today. In the current age of the life sciences, investigators have to interpret many types of information from a variety of sources: lab instruments, public databases, gene expression profiles, raw sequence traces, single nucleotide polymorphisms, chemical screening data, proteomic data, putative metabolic pathway models, and many others. Unfortunately, scientists are not currently able to easily identify and access this information because of the variety of semantics, interfaces, and data formats used by the underlying data sources.

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Barbara Gastel, physician and acclaimed medical journalist, has prepared an expanded, enhanced second edition of Health Writer's Handbook. Fully updated, the latest edition of this trusted handbook has grown by nearly 100 pages, solidifying its reputation as a "practical guide packed with specifics on how to write about health intelligently and with sensitivity" (Nieman Reports). Examples of exemplary health writing now abound with insightful annotated comments. "Medical Reporting for the Electronic Media" (contributed by Tom Linden, M.D., University of North Carolina at Chapel Hill) addresses health reporting for television, radio, and the Internet. Also new to this edition is coverage of legal matters in the retitled "Ethical and Legal Issues" chapter. Journalistic exercises bring chapters to a close giving the reader opportunities to apply the principles presented. Health Writer's Handbook, Second Edition is a reference guide and textbook all in one, invaluable to experienced health writers looking to improve their writing and to students beginning their study in medical journalism.

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Due to the rising threat of tuberculosis and other mycobacterial infections, methods to study the biology of the mycobacteria and to improve diagnostic, therapeutic and preventative reagents are still very much in need.  Mycobacteria Protocols, Second Edition updates and refines the methods of the well-received first edition while adding newly developed methods culled from the most cutting-edge research in the field.  Ranging from the basics of sub-cellular fractionation to advanced methods using specialized growth conditions and whole genome, transcriptome and proteome analysis, the chapters conform to the Methods in Molecular Biology™ series format, providing step-by-step laboratory protocols, lists of necessary materials and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and up-to-date, Mycobacteria Protocols, Second Edition is the perfect resource to promote and stimulate further research into these intriguing, important and most fractious of bacteria.Read more Mycobacteria Protocols (Methods in Molecular Biology)

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"A great anthology. . . Discussions by the compilers are valuable."-Annals of Internal Medicine

"By publishing this book the Pan American Health Organization has done a big favor to those of us with an interest in the key events which have contributed to the development of epidemiology."-The Lancet

Edited by four eminent epidemiologists, this book consolidates, for the first time, a core of landmark articles on the evolution, scope and limitations, uses, and prospects of epidemiology. An outstanding feature of the book is the inclusion of the editors' assessments of the realm of epidemiology, where it is and where it should be going. It represents a useful tool for both students and practicing professionals and provides a much-needed frame of reference for reorienting the practice of epidemiology.

The book is a collection of 91 articles, grouped in five sections. The first two sections deal with the historical evolution of the discipline and sections 3 and 4 address the application of epidemiology. Finally, section 5 offers the editors views on epidemiology's future.