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This is the second edition of this text on logistic regression methods. As in the first edition, each chapter contains a presentation of its topic in "lecture-book" format together with objectives, an outline, key formulae, practice exercises, and a test. The "lecture-book" has a sequence of illustrations and formulae in the left column of each page and a script (i.e., text) in the right column. This format allows you to read the script in conjunction with the illustrations and formulae that highlight the main points, formulae, or examples being presented. This second edition includes five new chapters and an appendix. The new chapters are: Chapter 9. Polytomous Logistic Regression Chapter 10. Ordinal Logistic Regression Chapter 11. Logistic Regression for Correlated Data Chapter 12. GEE Examples Chapter 13. Other Approaches for Analysis of Correlated Data Chapters 9 and 10 extend logistic regression to response variables that have more than two categories. Chapters 11-13 extend logistic regression to generalized estimating equations (GEE) and other methods for analyzing correlated response data. The appendix "Computer Programs for Logistic Regression" provides descriptions and examples of computer programs for carrying out the variety of logistic regression procedures described in the main text. The software packages considered are SAS Version 8.0, SPSS Version 10.0 and STATA Version 7.0.

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Here is a unified, readable introduction to multipredictor regression methods in biostatistics, including linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, and generalized linear models for counts and other outcomes. The authors describe shared elements in methods for selecting, estimating, checking, and interpreting each model, and show that these regression methods deal with confounding, mediation, and interaction of causal effects in essentially the same way.

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This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for longitudinal and hierarchical outcomes, and generalized linear models for counts and other outcomes. Treating these topics together takes advantage of all they have in common. The authors point out the many-shared elements in the methods they present for selecting, estimating, checking, and interpreting each of these models. They also show that these regression methods deal with confounding, mediation, and interaction of causal effects in essentially the same way. The examples, analyzed using Stata, are drawn from the biomedical context but generalize to other areas of application. While a first course in statistics is assumed, a chapter reviewing basic statistical methods is included. Some advanced topics are covered but the presentation remains intuitive. A brief introduction to regression analysis of complex surveys and notes for further reading are provided.

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Applied Survival Analysis: Regression Modeling of Time to Event Data (Wiley Series in Probability and Statistics) Reviews

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THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING TIME-TO-EVENT DATA—NOW IN A VALUABLE NEW EDITION

Since publication of the first edition nearly a decade ago, analyses using time-to-event methods have increase considerably in all areas of scientific inquiry mainly as a result of model-building methods available in modern statistical software packages. However, there has been minimal coverage in the available literature to9 guide researchers, practitioners, and students who wish to apply these methods to health-related areas of study. Applied Survival Analysis, Second Edition provides a comprehensive and up-to-date introduction to regression modeling for time-to-event data in medical, epidemiological, biostatistical, and other health-related research.

This book places a unique emphasis on the practical and contemporary applications of regression modeling rather than the mathematical theory. It offers a clear and accessible presentation of modern modeling techniques supplemented with real-world examples and case studies. Key topics covered include: variable selection, identification of the scale of continuous covariates, the role of interactions in the model, assessment of fit and model assumptions, regression diagnostics, recurrent event models, frailty models, additive models, competing risk models, and missing data.

Features of the Second Edition include:

• Expanded coverage of interactions and the covariate-adjusted survival functions
• The use of the Worchester Heart Attack Study as the main modeling data set for illustrating discussed concepts and techniques
• New discussion of variable selection with multivariable fractional polynomials
• Further exploration of time-varying covariates, complex with examples
• Additional treatment of the exponential, Weibull, and log-logistic parametric regression models
• Increased emphasis on interpreting and using results as well as utilizing multiple imputation methods to analyze data with missing values
• New examples and exercises at the end of each chapter

Analyses throughout the text are performed using Stata® Version 9, and an accompanying FTP site contains the data sets used in the book. Applied Survival Analysis, Second Edition is an ideal book for graduate-level courses in biostatistics, statistics, and epidemiologic methods. It also serves as a valuable reference for practitioners and researchers in any health-related field or for professionals in insurance and government.

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