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As those in medicine increasingly depend on computers and other intelligent machines, the intersection of ethics, computing and the health professions grows much more complex and significant. This book attempts to systematically identify and address the full range of ethical issues that arise when intelligent machines are used in medicine, nursing, psychology, and allied health professions. It explores a variety of important issues, including ethics and evaluation in computational medicine; patient and provider confidentiality; responsibility for use of computers in medicine; appropriate use of decision support systems; outcomes research and computational prognosis (including mortality predictions); and computer-based biomedical research--especially meta-analysis. It is accessible to professionals and students in the fields of bioethics and medical informatics.

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Exploitation and Developing Countries: The Ethics of Clinical Research

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When is clinical research in developing countries exploitation? Exploitation is a concept in ordinary moral thought that has not often been analyzed outside the Marxist tradition. Yet it is commonly used to describe interactions that seem morally suspect in some way. A case in point is clinical research sponsored by developed countries and carried out in developing countries, with participants who are poor and sick, and lack education. Such individuals seem vulnerable to abuse. But does this, by itself, make such research exploitative?

Exploitation and Developing Countries is an attempt by philosophers and bioethicists to reflect on the meaning of exploitation, to ask whether and when clinical research in developing countries counts as exploitative, and to consider what can be done to minimize the possibility of exploitation in such circumstances. These reflections should interest clinical researchers, since locating the line between appropriate and inappropriate use of subjects--the line between exploitation and fair use--is the central question at the heart of research ethics. Reflection on this rich and important moral concept should also interest normative moral philosophers of a non-Marxist bent.

In addition to the editors, the contributors are Richard J. Arneson, Alisa L. Carse, Margaret Olivia Little, Thomas Pogge, Andrew W. Siegel, and Alan Wertheimer.

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The authors of this book examine critically, and in a unique way, the poverty of medical ethics. They argue against spending almost unlimited amounts of money on medical treatment, and explore the serious biases in the way that medical research is conducted. In particular, they document how commercialization of research, especially in the pharmaceutical industry, leads to seriously distorted information being disseminated to physicians. The authors illustrate these problems using four examples: statin drugs, screening for breast and prostate cancer, genetic diagnosis and therapy, and the Swan ganz catheter. The book contrasts the greatly exaggerated merits of these medical practices with the clear advantages of a prevention approach. The book makes radical proposals for reforming these problems. It is a must-read for those interested in medical ethics, health policy, health economics, and medicine.

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Case Studies in Biomedical Research Ethics (Basic Bioethics) Description

This textbook for instruction in biomedical research ethics can also serve as a valuable reference for professionals in the field of bioethics. The 149 cases included in the book are grouped in nine chapters, each of which covers a key area of debate in the field. Some of the case studies are classics, including the famous cases of the Tuskegee Syphilis Study (in which subjects with syphilis were not given treatment) and the Willowbrook hepatitis studies (in which institutionalized subjects were intentionally exposed to hepatitis). Others focus on such current issues as human embryonic stem cell research, cloning by somatic nuclear transfer, and the design and function of institutional review boards. Each chapter begins with a brief introduction that places the issues raised in context; this is followed by a number of cases (each of which is no more than a few pages). Study questions meant to encourage further discussion follow each case.After an introductory discussion of the history and tenets of ethics in medical research, the book's chapters cover the topics of oversight and study design; informed consent; the selection of subjects; conflicts of interest; the social effects of research; embryos, fetuses, and children; genetic research; the use of animals; and authorship and publication. Following these chapters are appendixes with the texts of the Nuremburg Code and the World Declaration of Geneva, two key documents in the establishment of bioethical standards for research. Also included are a glossary, a table of cases by general category, and an alphabetical listing of cases.