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Like other books in the Laboratory Animal Pocket Reference Series, this guide covers all aspects pertaining to the use of these organisms including their basic biology, humane care and management, husbandry, life support systems, regulatory compliance, technical procedures, veterinary care, and water quality management.

In the relatively brief span of only a few decades, the zebrafish has gone from being mainly a hobby fish to a mainstream model animal employed by scientists to study everything from stem cells to the basis of behavioral changes induced by drug addiction. This rapid advance has been fueled largely by numerous and impressive advances in technology, along with detailed characterization of the animal on a genetic and molecular level. These developments have allowed scientists to leverage the many advantages of the zebrafish system to address many important questions in biology and human genetics and disease.

However, there are few accepted and established standards for husbandry, management, and care for the fish in laboratory settings and even fewer comprehensive and constantly reliable resources. To this end, the goal of this handbook is to provide managers, veterinarians, investigators, technicians, and regulatory personnel with a concise yet thorough reference on zebrafish biology, care, husbandry, and management.

The aim of the book is not to set standards, but rather to arm those working with the fish with scientifically grounded principles and fundamental information that can be used to design sound fish care programs. This handbook is organized into seven chapters:

Biology
Husbandry
Life Support Systems
Management
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Experimental Methodology
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The final chapter, Resources, provides the zebrafish user with lists of sources of additional information on the zebrafish model, as well as key references, professional organizations, and suppliers of equipment and supplies used in zebrafish husbandry and care.

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Selected FDA GCP/Clinical Trial Guidance Documents Grouped by Topic: * FDA Overview and Orientation * Introduction to GCP * Part I: General * Part II: Institutional Review Boards (IRBs) and Informed Consent * Part III: Drugs and Biologics * Part IV: Medical Devices * Part V: Manufacturing Requirements for Investigational Products * Part VI: Electronic Data Reference Tools * Part VII: Combined Glossary and Index for all Quality Guidance Documents

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James L. Harner's Literary Research Guide, which Choice calls "the standard guide in the field," evaluates important reference materials in English studies. Since the publication of the first edition in 1989, tens of thousands of students and educators have used the Guide as an aid to scholarly research. Harner has added entries describing resources published since 1997 and has revised nearly half the entries from the third edition. The fourth edition contains more than 1,200 entries, which discuss an additional 1,494 books, articles, and electronic resources and cite 729 reviews. New entries reflect the expansion of literary study into emerging fields (gay, lesbian, and transgendered studies and postcolonial theory); this edition also lists reliable Web sites sponsored by academic institutions and learned societies. The annotations describe the type of work, its scope, its major limitations, and its organization present parts of a typical entry in the work list the type and number of indexes evaluate coverage, organization, and accuracy explain the work's uses in research cite significant reviews that more fully define the importance or uses of the work or its place in the scholarly tradition note related works, including supplementary, complementary, or superseded ones not accorded separate entries in the Guide The Guide concludes with name, title, and subject indexes.Read more Literary Research Guide: An Annotated Listing of Reference Sources in English Literary Studies

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Even though Xenopus is one of the two most popular non-mammalian animals used in biomedical research, its value in the lab suffers from a lack of standardization regarding their optimal care, breeding, and housing.

Filling the need for such a reference, The Laboratory Xenopus sp provides researchers and lab managers with a practical, step-by-step manual that emphasizes the humane care and use of captive clawed frogs in basic as well as biomedical, and toxicological research.

The Only Book of Its Kind Available to Researchers

Amply illustrated with 50 color illustrations of management practices and technical procedures, this how-to guide:

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• Illustrates management practices and technical procedures with figures and tables
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Supported with hypothesis-driven research, this well-organized manual explores the full range of responsibilities facing individuals who work with this species. The content is divided into intentionally brief sections that allow for the quick retrieval of essential information regarding important biological features and experimental methodology, as well as compliance and veterinary care, husbandry, housing, and water quality management.

The book has an accompanying website with more information, including interesting frog trivia.

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