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With this new edition, Science and Technical Writing confirms its position as the definitive style resource for thousands of established and aspiring technical writers. Editor Philip Rubens has fully revised and updated his popular 1992 edition, with full, authoritative coverage of the techniques and technologies that have revolutionized electronic communications over the past eight years.

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This book analyses patterns in rural China in the late 1980s: patterns of causes of death, of what people ate, what they smoked and drank, what kinds of houses they lived in, what they worked at, their education, and many measurements of their blood (for cholesterol, vitamins, evidence of infectious disease) and urine (for food metabolites and other factors). The variation is examined at the level of counties scattered all over mainland China and Taiwan, representing the extremes of values for deaths from specific cancers; ie the counties with the highest and the lowest rates of lung cancer, or the highest and lowest for liver cancer. Coincidentally, this covers the extremes of many of the other variables, such as the intake of fresh fruits and vegetables, and smoking rates. The analysis that fills the pages is the correlation of all of these patterns, one variable at a time, with all the others. The question it answers is, "How well does the variation among the counties for one variable (eg cholesterol in the blood) correlate with the variation across China in deaths from different diseases (eg heart disease)?". If the correlation is strong, it may mean that the variables are related in some causal sense, although this cannot be assumed. If the correlation is weak, it means that the variation must be caused mainly by other factors. Importantly, if the correlation is weak, it does not necessarily mean that the two variables are not related; for example, a weak correlation between blood cholesterol and deaths from heart disease does not mean that cholesterol is not implicated in heart disease, but that in China other factors are more important. Each variable page is similarly arranged, and there are keys to interpreting each element at the beginning of major sections. The book also includes numerous extra tables in the back that give mean values for many variables. These can be useful as many of these values in China are so different from the much more available and common Western values. We tend to think of the range of Western variables as somehow 'normal', without realizing that in China the mean value may not even be within the generally accepted normal range that we are used to.

Best Study Guide to Epidemiology And Biostatistics (Study Guide to Epidemiology and Biostatistics)

Study Guide to Epidemiology And Biostatistics (Study Guide to Epidemiology and Biostatistics) by Jones & Bartlett Learning




Perfect for graduate and undergraduate students, this book helps the reader understand some of the most elusive fundamentals of epidemiology and biostatistics. The sixth edition has been thoroughly revised and further clarifies difficult concepts such as person-time incidence rates, confounding, effect modification, P values, and survival analysis. The authors have also covered new topics that are increasingly seen in current literature such as attributable risk, the use of odds and the application of probabilistic concepts in epidemiology, the reliability of screening tests, and longitudinal regression models. Features: 46 objectives, expressed in behavioral terms, cite the concepts to be learned and the level at which students are expected to perform A final chapter which introduces a systematic procedure to aid the student in the evaluation of health science articles Study Notes, which can be used as the sole source of input to cover the material or used to supplement attendance at a lecture series Chapter Exercises, which encourage students to immediately use their newly acquired knowledge, and thus improve retention through practice Multiple Choice Examinations, which have the same scope and are on the same level that students may expect to encounter in professional examinationsRead more Study Guide to Epidemiology And Biostatistics (Study Guide to Epidemiology and Biostatistics)

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Ideal for clinical students including medical, nursing, pharmacy, dental, physician assistant and more!

Evidence-based information plays a critical role in clinical practice decisions. Secondary sources are often unreliable; it’s up to the student, then, to critically assess peer-reviewed research literature. Using a highly structured yet accessible method, this best-selling text teaches students to critically analyze research from primary sources.

Step-by-step approach– learn to recognize a meaningful study, clues to potential study flaws, and ways to apply solid evidence in clinical practice

Simple 6-point framework– learn to evaluate studies in terms of the author’s trademark mnemonic device, M.A.A.R.I.E. (Methods, Assignment, Assessment, Results, Interpretation and Extrapolation)

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Interpreting Epidemiologic Evidence: Strategies for Study Design and Analysis Best Reviews

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Evaluating the strength or persuasiveness of epidemiologic evidence is inherently challenging, both for those new to the field and for experienced researchers. There are a myriad of potential biases to consider, but little guidance about how to asses the likely impact on study results. This book offers a strategy for assessing epidemiologic research findings, explicitly describing the goals and products of epidemiologic research in order to better evaluate it successes and limitations. The focus throughout is on practical tools for making optimal use of available data to assess whether hypothesized biases are operative and to anticipate concerns at the point of study design in order to ensure that needed information is generated. Specific tools for assessing the presence and impact of selection bias in both cohort and case-control studies, bias from non-response, confounding, exposure measurement error, disease measurement error, and random error are identified and evaluated. The potential value of each approach as well as its limitations are discussed, using examples from the published literature. Such information should help those who generate and interpret epidemiologic research to apply methodological principles more effectively to substantive issues, leading to a more accurate appraisal of the current evidence and greater clarity about research needs.

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+++ Epidemiology: Study Design and Data Analysis, Second Edition (Chapman & Hall/CRC Texts in Statistical Science)

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Building an up-to-date understanding of the methodologies that can be used to shape public health policies, Epidemiology: Study Design and Data Analysis, Second Edition encompasses the study of epidemiology from the observation of associations between risk factors and disease to the use of practical, data-supported analyses. It presents study designs commonly used for a wide range of purposes, and covers the spectrum of statistical principles and analytical tools used in epidemiological research, such as techniques used in report writing, descriptive analyses, statistical models and synthesis of evidence.

New Material in This Edition Includes:

Systematic evaluation

Meta-analysis

Regression dilution

Case-cohort studies

Case-crossover studies

Pooled logistic regression

Companion Web site containing data sets for examples and exercises, SAS and Stata code for examples, a sample size calculator, and a SAS floating absolute risk macro

The second edition of a popular textbook, this book emphasizes quantitative and design aspects of epidemiological research. The author favors the use of basic mathematics and practical methods over complicated mathematical proofs, making this an ideal textbook that is comprehensive yet accessible to graduate students in epidemiology, statistics, public health studies, and/or medical research.

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Best Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators

Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators by Mountainside MD Press




Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators, 2nd edition, is a step-by-step how-to manual for both experienced medical professionals and novices looking to enter the field of clinical studies.

Explains how to land a study on good terms

Provides tips for recruiting patient volunteers--and keeping them happy

Offers easy strategies for coordinating studies

Demystifies regulatory requirements

With a comprehensive index and appendices, this book has been adopted by university health sciences programs across the country.

The first edition was a Ben Franklin Awards 2007 Finalist and a 2007 Finalist in ForeWord Magazine's reference category for professional/technical books.

New, expanded, and completely updated sections keep readers abreast of changes in the rapidly shifting global drug development industry, including new regulations affecting research, subject injury clauses, the unique needs of device and vaccine trials, the impact of HIPAA on U.S. research, cultural competency and health literacy, ethical considerations in clinical research, and how to survive audits.Read more Conducting Clinical Research: A Practical Guide for Physicians, Nurses, Study Coordinators, and Investigators

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"This book is a superior achievement from a group of masterful scholars. The book shows the theoretical, ethical, and political complexity of qualitative study, and yet offers an illuminating and useful guide to how it can be accomplished with distinction. I highly recommend it."

—MARGARETE SANDELOWSKI, PhD, RN, FAAN

Professor, School of Nursing

University of North Carolina at Chapel Hill

In this book, Volume 3 of the Methods in Nursing Research series, Barbara Paterson and colleagues provide step-by-step directions for how to proceed in conducting a meta-study, as well as recommendations for tools and standards relating to the application of their approach. Drawing from their experience with meta-study research projects on chronic illness, the authors articulate and theorize the meta-analysis and meta-synthesis of qualitatively derived knowledge.

 

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The forty-year "Tuskegee" Syphilis Study has become the American metaphor for medical racism, government malfeasance, and physician arrogance. The subject of histories, films, rumors, and political slogans, it received an official federal apology from President Bill Clinton in a White House ceremony.

Susan M. Reverby offers a comprehensive analysis of the notorious study of untreated syphilis, which took place in and around Tuskegee, Alabama, from the 1930s through the 1970s. The study involved hundreds of African American men, most of whom were told by the doctors from the U.S. Public Health Service that they were being treated, not just watched, for their late-stage syphilis. Reverby examines the study and its aftermath from multiple perspectives to explain what happened and why the study has such power in collective memory. She follows the study's repercussions in facts and fictions.

Reverby highlights the many uncertainties that dogged the study during its four decades and explores the newly available medical records. She uncovers the different ways it was understood by the men, their families, and the health care professionals, ultimately revising the conventional wisdom on the study.

Writing with rigor and clarity, Reverby illuminates the events and aftermath of the study and sheds light on the complex knot of trust, betrayal, and belief that keeps this study alive in our cultural and political lives.

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Best Evaluating Clinical and Public Health Interventions: A Practical Guide to Study Design and Statistics

Evaluating Clinical and Public Health Interventions: A Practical Guide to Study Design and Statistics by Cambridge University Press




Whether you are evaluating the effectiveness of a drug, a medical device, a behavioral intervention, a community mobilization, or even a new law, this is the book for you. Written in plain language, it simplifies the process of designing interventions, analyzing the data, and publishing the results. Because the choice of research design depends on the nature of the intervention, the book covers randomized and nonrandomized designs, prospective and retrospective studies, planned clinical trials and observational studies. In addition to reviewing standard statistical analysis, the book has easy-to-follow explanations of cutting edge techniques for evaluating interventions, including propensity score analysis, instrumental variable analysis, interrupted time series analysis and sensitivity analysis. All techniques are illustrated with up-to-date examples from medical and public health literature. This will be essential reading for a wide range of healthcare professionals involved in research as well as those more specifically interested in public health issues and epidemiology.Read more Evaluating Clinical and Public Health Interventions: A Practical Guide to Study Design and Statistics

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Best Study Design and Statistical Analysis: A Practical Guide for Clinicians

Study Design and Statistical Analysis: A Practical Guide for Clinicians by Cambridge University Press




This book takes the reader through the entire research process: choosing a question, designing a study, collecting the data, using univariate, bivariate and multivariable analysis, and publishing the results. It does so by using plain language rather than complex derivations and mathematical formulas. It focuses on the nuts and bolts of performing research by asking and answering the most basic questions about doing research studies. Making good use of numerous tables, graphs and tips, this book helps to demystify the process. A generous number of up-to-date examples from the clinical literature give an illustrated and practical account of how to use multivariable analysis.Read more Study Design and Statistical Analysis: A Practical Guide for Clinicians

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Examining the principles and methods of research on the evaluation of factors affecting the outcome of illness, this book emphasizes diagnostic and therapeutic interventions--the factors most readily modified by health care providers. The author discusses various ways of structuring observations on patient groups, and appraises the nature and strength of inferences drawn from those observations. He also demonstrates how the results of this type of research--clinical epidemiologic research--can be incorporated into the decision-making process utilized in clinical medicine.

This book contains a concise account of topics such as the assessment of the use of diagnostics and screening tests and their role in improving the outcome of illness, the evaluation of therapeutic efficacy through experimental and nonexperimental studies, and a particularly useful chapter on assessment of therapeutic safety. It is an essential reference and guide to the quantitative assessment of the consequences of illness for clinicians in training or in practice.The new edition of Clinical Epidemiology greatly expands the chapter on randomized control trials, and includes a whole new chapter on meta-analysis, authored by Peter Cummings. Meta-analysis, the statistical synthesis of data from comparable studies, was unheard of 30 years ago, but with the advent of increased computer technology, the method has been steadily growing in importance in the epidemiology community.